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Analysis of kinetic data for irreversible enzyme inhibition.

Many organophosphorus compounds are irreversible inhibitors of acetylcholinesterase. The methods used in the literature to determine the inhibition kinetic constants usually involve either manual determination of the slope at various points along the inhibition progress curve or fitting polynomials...

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Detalhes bibliográficos
Main Authors: Gray, P J, Duggleby, R G
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1135596/
https://ncbi.nlm.nih.gov/pubmed/2930459
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