Identification of Penicillin Binding Protein 4 (PBP4) as a critical factor for Staphylococcus aureus bone invasion during osteomyelitis in mice

Staphylococcus aureus infection of bone is challenging to treat because it colonizes the osteocyte lacuno-canalicular network (OLCN) of cortical bone. To elucidate factors involved in OLCN invasion and identify novel drug targets, we completed a hypothesis-driven screen of 24 S. aureus transposon in...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:PLoS Pathog
Hlavní autoři: Masters, Elysia A., de Mesy Bentley, Karen L., Gill, Ann Lindley, Hao, Stephanie P., Galloway, Chad A., Salminen, Alec T., Guy, Diamond R., McGrath, James L., Awad, Hani A., Gill, Steven R., Schwarz, Edward M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7608983/
https://ncbi.nlm.nih.gov/pubmed/33091079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008988
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky