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p53 directly represses human LINE1 transposons
p53 is a potent tumor suppressor and commonly mutated in human cancers. Recently, we demonstrated that p53 genes act to restrict retrotransposons in germline tissues of flies and fish but whether this activity is conserved in somatic human cells is not known. Here we show that p53 constitutively res...
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| Publicado no: | Genes Dev |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7608743/ https://ncbi.nlm.nih.gov/pubmed/33060137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.343186.120 |
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