Heritability of the HIV-1 reservoir size and decay under long-term suppressive ART

The HIV-1 reservoir is the major hurdle to curing HIV-1. However, the impact of the viral genome on the HIV-1 reservoir, i.e. its heritability, remains unknown. We investigate the heritability of the HIV-1 reservoir size and its long-term decay by analyzing the distribution of those traits on viral...

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Publicado no:Nat Commun
Main Authors: Wan, Chenjie, Bachmann, Nadine, Mitov, Venelin, Blanquart, François, Céspedes, Susana Posada, Turk, Teja, Neumann, Kathrin, Beerenwinkel, Niko, Bogojeska, Jasmina, Fellay, Jacques, Roth, Volker, Böni, Jürg, Perreau, Matthieu, Klimkait, Thomas, Yerly, Sabine, Battegay, Manuel, Walti, Laura, Calmy, Alexandra, Vernazza, Pietro, Bernasconi, Enos, Cavassini, Matthias, Metzner, Karin J., Günthard, Huldrych F., Kouyos, Roger D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7608612/
https://ncbi.nlm.nih.gov/pubmed/33139735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19198-7
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