Dissecting HIV Virulence: Heritability of Setpoint Viral Load, CD4+ T-Cell Decline, and Per-Parasite Pathogenicity

Pathogen strains may differ in virulence because they attain different loads in their hosts, or because they induce different disease-causing mechanisms independent of their load. In evolutionary ecology, the latter is referred to as “per-parasite pathogenicity”. Using viral load and CD4+ T-cell mea...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Mol Biol Evol
Κύριοι συγγραφείς: Bertels, Frederic, Marzel, Alex, Leventhal, Gabriel, Mitov, Venelin, Fellay, Jacques, Günthard, Huldrych F, Böni, Jürg, Yerly, Sabine, Klimkait, Thomas, Aubert, Vincent, Battegay, Manuel, Rauch, Andri, Cavassini, Matthias, Calmy, Alexandra, Bernasconi, Enos, Schmid, Patrick, Scherrer, Alexandra U, Müller, Viktor, Bonhoeffer, Sebastian, Kouyos, Roger, Regoes, Roland R
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Oxford University Press 2018
Θέματα:
Discoveries
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850767/
https://ncbi.nlm.nih.gov/pubmed/29029206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msx246
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