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Mutation screening of germline TP53 mutations in high-risk Chinese breast cancer patients

BACKGROUND: Germline TP53 mutations are associated with Li-Fraumeni syndrome, a severe and rare hereditary cancer syndrome. Despite the rarity of germline TP53 mutations, the clinical implication for mutation carriers and their families is significant. The risk management of TP53 germline mutation c...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Kwong, Ava, Shin, Vivian Yvonne, Ho, Cecilia Y. S., Au, Chun Hang, Slavin, Thomas P., Weitzel, Jeffrey N., Chan, Tsun-Leung, Ma, Edmond S. K.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7607817/
https://ncbi.nlm.nih.gov/pubmed/33138793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07476-y
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