Lonidamine potentiates the oncolytic efficiency of M1 virus independent of hexokinase 2 but via inhibition of antiviral immunity

BACKGROUND: Viruses are obligate parasites that depend on host cells to provide the energy and molecular precursors necessary for successful infection. The main component of virus-induced metabolic reprogramming is the activation of glycolysis, which provides biomolecular resources for viral replica...

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Publicat a:Cancer Cell Int
Autors principals: Cai, Jing, Zhu, Wenbo, Lin, Yuan, Hu, Jun, Liu, Xincheng, Xu, Wencang, Liu, Ying, Hu, Cheng, He, Songmin, Gong, Shoufang, Yan, Guangmei, Liang, Jiankai
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Primary Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7607643/
https://ncbi.nlm.nih.gov/pubmed/33292203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01598-w
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