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Telomerase reverse transcriptase promoter mutations in thyroid carcinomas: implications in precision oncology—a narrative review

Telomerase is a ribonucleoprotein enzyme with telomerase reverse transcriptase (TERT) as a catalytic component. In normal human follicular thyroid cells or thyrocytes, telomerase is silent due to the TERT gene being tightly repressed. However, during the formation of thyroid carcinoma (TC), telomera...

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Detaylı Bibliyografya
Yayımlandı:Ann Transl Med
Asıl Yazarlar: Yuan, Xiaotian, Liu, Tiantian, Xu, Dawei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: AME Publishing Company 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7607115/
https://ncbi.nlm.nih.gov/pubmed/33178776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-20-5024
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