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Telomerase reverse transcriptase promoter mutations in thyroid carcinomas: implications in precision oncology—a narrative review
Telomerase is a ribonucleoprotein enzyme with telomerase reverse transcriptase (TERT) as a catalytic component. In normal human follicular thyroid cells or thyrocytes, telomerase is silent due to the TERT gene being tightly repressed. However, during the formation of thyroid carcinoma (TC), telomera...
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| Publicado no: | Ann Transl Med |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
AME Publishing Company
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7607115/ https://ncbi.nlm.nih.gov/pubmed/33178776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-20-5024 |
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