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ATG16L1 autophagy pathway regulates BAX protein levels and programmed cell death

Previously we reported that adipocyte SNAP23 (synaptosome-associated protein of 23 kDa) deficiency blocks the activation of macroautophagy, leading to an increased abundance of BAX, a pro-death Bcl-2 family member, and activation and adipocyte cell death both in vitro and in vivo. Here, we found tha...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Chen, Fenfen, Amgalan, Dulguun, Kitsis, Richard N., Pessin, Jeffrey E., Feng, Daorong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606669/
https://ncbi.nlm.nih.gov/pubmed/32848017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013999
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