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Brain uptake pharmacokinetics of incretin receptor agonists showing promise as Alzheimer’s and Parkinson’s disease therapeutics

Among the more promising treatments proposed for Alzheimer’s disease (AD) and Parkinson’s disease (PD) are those reducing brain insulin resistance. The antidiabetics in the class of incretin receptor agonists (IRAs) reduce symptoms and brain pathology in animal models of AD and PD, as well as glucos...

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Vydáno v:Biochem Pharmacol
Hlavní autoři: Salameh, Therese S., Rhea, Elizabeth M., Talbot, Konrad, Banks, William A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606641/
https://ncbi.nlm.nih.gov/pubmed/32755557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2020.114187
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