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Brain uptake pharmacokinetics of incretin receptor agonists showing promise as Alzheimer’s and Parkinson’s disease therapeutics

Among the more promising treatments proposed for Alzheimer’s disease (AD) and Parkinson’s disease (PD) are those reducing brain insulin resistance. The antidiabetics in the class of incretin receptor agonists (IRAs) reduce symptoms and brain pathology in animal models of AD and PD, as well as glucos...

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Detalhes bibliográficos
Publicado no:Biochem Pharmacol
Main Authors: Salameh, Therese S., Rhea, Elizabeth M., Talbot, Konrad, Banks, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606641/
https://ncbi.nlm.nih.gov/pubmed/32755557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2020.114187
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