Human pediatric B-cell acute lymphoblastic leukemias can be classified as B-1 or B-2-like based on a minimal transcriptional signature

The finding that transformed mouse B-1 and B-2 progenitors give rise to B-cell acute lymphoblastic leukemias (B-ALLs) with varied aggressiveness suggests that B cell lineage might also be a factor in the initiation and progression of pediatric B-ALLs in humans. If this is the case, we hypothesized t...

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Библиографические подробности
Опубликовано в: :Exp Hematol
Главные авторы: Fitch, Briana, Roy, Ritu, Geng, Huimin, Montecino-Rodriguez, Encarnacion, Bengtsson, Henrik, Gaillard, Coline, Hiam, Kamir, Casero, David, Olshen, Adam B., Dorshkind, Kenneth, Kogan, Scott C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606616/
https://ncbi.nlm.nih.gov/pubmed/32946981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2020.09.184
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