Opsonized antigen activates Vδ2+ T cells via CD16/FCγRIIIa in individuals with chronic malaria exposure

Vγ9Vδ2 T cells rapidly respond to phosphoantigens produced by Plasmodium falciparum in an innate-like manner, without prior antigen exposure or processing. Vδ2 T cells have been shown to inhibit parasite replication in vitro and are associated with protection from P. falciparum parasitemia in vivo....

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Farrington, Lila A., Callaway, Perri C., Vance, Hilary M., Baskevitch, Kayla, Lutz, Emma, Warrier, Lakshmi, McIntyre, Tara I., Budker, Rachel, Jagannathan, Prasanna, Nankya, Felistas, Musinguzi, Kenneth, Nalubega, Mayimuna, Sikyomu, Ester, Naluwu, Kate, Arinaitwe, Emmanuel, Dorsey, Grant, Kamya, Moses R., Feeney, Margaret E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605717/
https://ncbi.nlm.nih.gov/pubmed/33085728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008997
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