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Aggregation by peptide conjugation rescues poor immunogenicity of the HA stem

Influenza virus infection is a global public health threat. Current seasonal influenza vaccines are efficacious only when vaccine strains are matched with circulating strains. There is a critical need for developing “universal” vaccines that protect against all influenza viruses. HA stem is a promis...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Jiang, Wenbo, Pilkington, Emily H., Kelly, Hannah G., Tan, Hyon-Xhi, Juno, Jennifer A., Wheatley, Adam K., Kent, Stephen J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605677/
https://ncbi.nlm.nih.gov/pubmed/33137148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0241649
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