Interferon Regulatory Factor-1 (IRF1) activates autophagy to promote liver ischemia/reperfusion injury by inhibiting β-catenin in mice

Autophagy is an important factor in liver ischemia-reperfusion injury. In the current study we investigate the function of interferon regulatory factor-1 (IRF1) in regulating autophagy to promote hepatic ischemia reperfusion injury (IR). The high expression of IRF1 during hepatic IR exhibited increa...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yan, Bing, Luo, Jing, Kaltenmeier, Christof, Du, Qiang, Stolz, Donna B., Loughran, Patricia, Yan, Yihe, Cui, Xiao, Geller, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605671/
https://ncbi.nlm.nih.gov/pubmed/33137133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239119
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