Fbxo2 mediates clearance of damaged lysosomes and modifies neurodegeneration in the Niemann-Pick C brain

A critical response to lysosomal membrane permeabilization (LMP) is the clearance of damaged lysosomes through a selective form of macroautophagy known as lysophagy. Although regulators of this process are emerging, whether organ- and cell-specific components contribute to the control of lysophagy r...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JCI Insight
Egile Nagusiak: Liu, Elaine A., Schultz, Mark L., Mochida, Chisaki, Chung, Chan, Paulson, Henry L., Lieberman, Andrew P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2020
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605537/
https://ncbi.nlm.nih.gov/pubmed/32931479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.136676
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