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Graph-Based Genome Alignment and Genotyping with HISAT2 and HISAT-genotype

Rapid advances in next-generation sequencing technologies have dramatically changed our ability to perform genome-scale analyses. The human reference genome used for most genomic analyses represents only a small number of individuals, limiting its usefulness for genotyping. We designed a novel metho...

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Publicat a:Nat Biotechnol
Autors principals: Kim, Daehwan, Paggi, Joseph M., Park, Chanhee, Bennett, Christopher, Salzberg, Steven L.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605509/
https://ncbi.nlm.nih.gov/pubmed/31375807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-019-0201-4
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