Role of Hypoxia-Inducible Factors in Regulating Right Ventricular Function and Remodeling during Chronic Hypoxia–induced Pulmonary Hypertension

Pulmonary hypertension (PH) and right ventricular (RV) hypertrophy frequently develop in patients with hypoxic lung disease. Chronic alveolar hypoxia (CH) promotes sustained pulmonary vasoconstriction and pulmonary artery (PA) remodeling by acting on lung cells, resulting in the development of PH. R...

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Bibliografische gegevens
Gepubliceerd in:Am J Respir Cell Mol Biol
Hoofdauteurs: Smith, Kimberly A., Waypa, Gregory B., Dudley, V. Joseph, Budinger, G. R. Scott, Abdala-Valencia, Hiam, Bartom, Elizabeth, Schumacker, Paul T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Thoracic Society 2020
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605159/
https://ncbi.nlm.nih.gov/pubmed/32692928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2020-0023OC
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