Long‐term expansion with germline potential of human primordial germ cell‐like cells in vitro

Human germ cells perpetuate human genetic and epigenetic information. However, the underlying mechanism remains elusive, due to a lack of appropriate experimental systems. Here, we show that human primordial germ cell‐like cells (hPGCLCs) derived from human‐induced pluripotent stem cells (hiPSCs) ca...

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Vydáno v:EMBO J
Hlavní autoři: Murase, Yusuke, Yabuta, Yukihiro, Ohta, Hiroshi, Yamashiro, Chika, Nakamura, Tomonori, Yamamoto, Takuya, Saitou, Mitinori
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604613/
https://ncbi.nlm.nih.gov/pubmed/32954504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020104929
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