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In vivo mRNA display enables large-scale proteomics by next generation sequencing

Large-scale proteomic methods are essential for the functional characterization of proteins in their native cellular context. However, proteomics has lagged far behind genomic approaches in scalability, standardization, and cost. Here, we introduce in vivo mRNA display, a technology that converts a...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Oikonomou, Panos, Salatino, Roberto, Tavazoie, Saeed
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604504/
https://ncbi.nlm.nih.gov/pubmed/33037152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2002650117
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