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In vivo mRNA display enables large-scale proteomics by next generation sequencing

Large-scale proteomic methods are essential for the functional characterization of proteins in their native cellular context. However, proteomics has lagged far behind genomic approaches in scalability, standardization, and cost. Here, we introduce in vivo mRNA display, a technology that converts a...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Oikonomou, Panos, Salatino, Roberto, Tavazoie, Saeed
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604504/
https://ncbi.nlm.nih.gov/pubmed/33037152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2002650117
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