Strategies to enable large-scale proteomics for reproducible research

Reproducible research is the bedrock of experimental science. To enable the deployment of large-scale proteomics, we assess the reproducibility of mass spectrometry (MS) over time and across instruments and develop computational methods for improving quantitative accuracy. We perform 1560 data indep...

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Pubblicato in:Nat Commun
Autori principali: Poulos, Rebecca C., Hains, Peter G., Shah, Rohan, Lucas, Natasha, Xavier, Dylan, Manda, Srikanth S., Anees, Asim, Koh, Jennifer M. S., Mahboob, Sadia, Wittman, Max, Williams, Steven G., Sykes, Erin K., Hecker, Michael, Dausmann, Michael, Wouters, Merridee A., Ashman, Keith, Yang, Jean, Wild, Peter J., deFazio, Anna, Balleine, Rosemary L., Tully, Brett, Aebersold, Ruedi, Speed, Terence P., Liu, Yansheng, Reddel, Roger R., Robinson, Phillip J., Zhong, Qing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7393074/
https://ncbi.nlm.nih.gov/pubmed/32732981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17641-3
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