A Glutamine Insertion at Codon 432 of RpoB Confers Rifampicin Resistance in Mycobacterium tuberculosis

Tuberculosis (TB) is an infectious respiratory disease caused by Mycobacterium tuberculosis and one of the top 10 causes of death worldwide. Treating TB is challenging; successful treatment requires a long course of multiple antibiotics. Rifampicin (RIF) is a first-line drug for treating TB, and the...

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Publicado en:Front Microbiol
Autores principales: Lai, Li-Yin, Hsu, Li-Yu, Weng, Shang-Hui, Chung, Shuo-En, Ke, Hui-En, Lin, Tzu-Lung, Hsieh, Pei-Fang, Lee, Wei-Ting, Tsai, Hsing-Yuan, Lin, Wan-Hsuan, Jou, Ruwen, Wang, Jin-Town
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604305/
https://ncbi.nlm.nih.gov/pubmed/33193223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.583194
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