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Rifampicin can induce antibiotic tolerance in mycobacteria via paradoxical changes in rpoB transcription

Metrics commonly used to describe antibiotic efficacy rely on measurements performed on bacterial populations. However, certain cells in a bacterial population can continue to grow and divide, even at antibiotic concentrations that kill the majority of cells, in a phenomenon known as antibiotic tole...

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Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Zhu, Jun-Hao, Wang, Bi-Wei, Pan, Miaomiao, Zeng, Yu-Na, Rego, Hesper, Javid, Babak
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181997/
https://ncbi.nlm.nih.gov/pubmed/30310059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06667-3
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