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Rifampicin can induce antibiotic tolerance in mycobacteria via paradoxical changes in rpoB transcription

Metrics commonly used to describe antibiotic efficacy rely on measurements performed on bacterial populations. However, certain cells in a bacterial population can continue to grow and divide, even at antibiotic concentrations that kill the majority of cells, in a phenomenon known as antibiotic tole...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Zhu, Jun-Hao, Wang, Bi-Wei, Pan, Miaomiao, Zeng, Yu-Na, Rego, Hesper, Javid, Babak
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181997/
https://ncbi.nlm.nih.gov/pubmed/30310059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06667-3
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