A Glutamine Insertion at Codon 432 of RpoB Confers Rifampicin Resistance in Mycobacterium tuberculosis

Tuberculosis (TB) is an infectious respiratory disease caused by Mycobacterium tuberculosis and one of the top 10 causes of death worldwide. Treating TB is challenging; successful treatment requires a long course of multiple antibiotics. Rifampicin (RIF) is a first-line drug for treating TB, and the...

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Veröffentlicht in:Front Microbiol
Hauptverfasser: Lai, Li-Yin, Hsu, Li-Yu, Weng, Shang-Hui, Chung, Shuo-En, Ke, Hui-En, Lin, Tzu-Lung, Hsieh, Pei-Fang, Lee, Wei-Ting, Tsai, Hsing-Yuan, Lin, Wan-Hsuan, Jou, Ruwen, Wang, Jin-Town
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604305/
https://ncbi.nlm.nih.gov/pubmed/33193223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.583194
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