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Direct conversion of human fibroblasts into dopaminergic neuron-like cells using small molecules and protein factors
BACKGROUND: Generation of neurons is essential in cell replacement therapy for neurodegenerative disorders like Parkinson’s disease. Several studies have reported the generation of dopaminergic (DA) neurons from mouse and human fibroblasts by ectopic expression of transcription factors, in which gen...
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| Publicado no: | Mil Med Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7603706/ https://ncbi.nlm.nih.gov/pubmed/33129359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40779-020-00284-2 |
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