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SDE2 integrates into the TIMELESS-TIPIN complex to protect stalled replication forks
Protecting replication fork integrity during DNA replication is essential for maintaining genome stability. Here, we report that SDE2, a PCNA-associated protein, plays a key role in maintaining active replication and counteracting replication stress by regulating the replication fork protection comp...
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| Publicat a: | Nat Commun |
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| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7603486/ https://ncbi.nlm.nih.gov/pubmed/33127907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19162-5 |
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