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Examining the Frequency of the JAK2 (V617F) Mutation in Patients with Myeloproliferative Diseases in North Eastern Iran and the Effect of Treatment Intervention

BACKGROUND: Janus kinase 2 (JAK2) is a tyrosine kinase located in the cytoplasm that plays a critical role in the signal transduction of cytokines and growth hormones. The conversion of valine to phenylalanine at the polypeptide position 617 results in the JAK2 (V617F) mutation, which often found in...

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Библиографические подробности
Опубликовано в: :Rep Biochem Mol Biol
Главные авторы: Nasseri, Mojila, Keyfi, Fatemeh, Rahbarian, Raheleh, Rajabian, Majid, Abbaszadegan, Mohammad Reza
Формат: Artigo
Язык:Inglês
Опубликовано: Varastegan Institute for Medical Sciences 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7603260/
https://ncbi.nlm.nih.gov/pubmed/33178868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.29252/rbmb.9.2.188
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