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The Mismatch Repair System (MMR) in Head and Neck Carcinogenesis and Its Role in Modulating the Response to Immunotherapy: A Critical Review

SIMPLE SUMMARY: The dysfunction of the mismatch repair system, an important mechanism for the detection and correction of DNA replication mistakes, may often lead to instability in the length of specific genetic sequences, known as microsatellites, and to the accumulation of mutations. Microsatellit...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Cilona, Maria, Locatello, Luca Giovanni, Novelli, Luca, Gallo, Oreste
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7602801/
https://ncbi.nlm.nih.gov/pubmed/33081243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12103006
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