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The Mismatch Repair System (MMR) in Head and Neck Carcinogenesis and Its Role in Modulating the Response to Immunotherapy: A Critical Review

SIMPLE SUMMARY: The dysfunction of the mismatch repair system, an important mechanism for the detection and correction of DNA replication mistakes, may often lead to instability in the length of specific genetic sequences, known as microsatellites, and to the accumulation of mutations. Microsatellit...

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Dettagli Bibliografici
Pubblicato in:Cancers (Basel)
Autori principali: Cilona, Maria, Locatello, Luca Giovanni, Novelli, Luca, Gallo, Oreste
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7602801/
https://ncbi.nlm.nih.gov/pubmed/33081243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12103006
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