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The Mismatch Repair System (MMR) in Head and Neck Carcinogenesis and Its Role in Modulating the Response to Immunotherapy: A Critical Review

SIMPLE SUMMARY: The dysfunction of the mismatch repair system, an important mechanism for the detection and correction of DNA replication mistakes, may often lead to instability in the length of specific genetic sequences, known as microsatellites, and to the accumulation of mutations. Microsatellit...

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Библиографические подробности
Опубликовано в: :Cancers (Basel)
Главные авторы: Cilona, Maria, Locatello, Luca Giovanni, Novelli, Luca, Gallo, Oreste
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7602801/
https://ncbi.nlm.nih.gov/pubmed/33081243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12103006
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