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Brain-Targeted Delivery of Pre-miR-29b Using Lactoferrin-Stearic Acid-Modified-Chitosan/Polyethyleneimine Polyplexes

The efficacy of brain therapeutics is largely hampered by the presence of the blood–brain barrier (BBB), mainly due to the failure of most (bio) pharmaceuticals to cross it. Accordingly, this study aims to develop nanocarriers for targeted delivery of recombinant precursor microRNA (pre-miR-29b), fo...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Pharmaceuticals (Basel)
Main Authors: Pereira, Patrícia, Barreira, Maria, Cruz, Carla, Tomás, Joana, Luís, Ângelo, Pedro, Augusto Q., Queiroz, João A., Sousa, Fani
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7602608/
https://ncbi.nlm.nih.gov/pubmed/33076502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13100314
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