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FGF2-Derived PeptibodyF2-MMAE Conjugate for Targeted Delivery of Cytotoxic Drugs into Cancer Cells Overexpressing FGFR1

SIMPLE SUMMARY: Current approaches to treat cancer include eg. targeted therapies, employing agents, such as antibodies, aimed directly at molecules expressed in cancerous cells. Here we present a targeting molecule alternative to antibodies-peptibodyF2-composed of a peptide responsible for its targ...

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Publicat a:Cancers (Basel)
Autors principals: Jendryczko, Karolina, Chudzian, Julia, Skinder, Natalia, Opaliński, Łukasz, Rzeszótko, Jakub, Wiedlocha, Antoni, Otlewski, Jacek, Szlachcic, Anna
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7602595/
https://ncbi.nlm.nih.gov/pubmed/33076489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12102992
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