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The Effects of Divalent Cation-Chelated Prion Fibrils on the Immune Response of EOC 13.31 Microglia Cells

Transmissible spongiform encephalopathies (TSEs) are epidemic neurodegenerative diseases caused by prion proteins; in particular, they are induced by misfolded prion proteins (PrP(Sc)). PrP(Sc) tend to aggregate into insoluble amyloid prion fibrils (fPrP(WT)), resulting in apoptosis of neuron cells...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Jen, Huan-I, Lin, Zih-You, Guo, Jin-Xun, Lee, Cheng-I
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7602007/
https://ncbi.nlm.nih.gov/pubmed/33066249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9102285
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