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Divalent cation chelators citrate and EDTA unmask an intrinsic uncoupling pathway in isolated mitochondria
We demonstrate a suppression of ROS production and uncoupling of mitochondria by exogenous citrate in Mg(2+) free medium. Exogenous citrate suppressed H(2)O(2) emission and depolarized mitochondria. The depolarization was paralleled by the stimulation of respiration of mitochondria. The uncoupling a...
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| Publicado no: | J Bioenerg Biomembr |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5023464/ https://ncbi.nlm.nih.gov/pubmed/26971498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10863-016-9656-x |
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