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Overview of the Nucleic-Acid Binding Properties of the HIV-1 Nucleocapsid Protein in Its Different Maturation States

HIV-1 Gag polyprotein orchestrates the assembly of viral particles. Its C-terminus consists of the nucleocapsid (NC) domain that interacts with nucleic acids, and p1 and p6, two unstructured regions, p6 containing the motifs to bind ALIX, the cellular ESCRT factor TSG101 and the viral protein Vpr. T...

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Detalles Bibliográficos
Publicado en:Viruses
Main Authors: Mouhand, Assia, Pasi, Marco, Catala, Marjorie, Zargarian, Loussiné, Belfetmi, Anissa, Barraud, Pierre, Mauffret, Olivier, Tisné, Carine
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601788/
https://ncbi.nlm.nih.gov/pubmed/33003650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12101109
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