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Endoplasmic Reticulum Stress Affects Cholesterol Homeostasis by Inhibiting LXRα Expression in Hepatocytes and Macrophages

Atherosclerosis (AS) is the most common cardiovascular disease, and reverse cholesterol transport (RCT) plays an important role in maintaining cholesterol homeostasis. Both endoplasmic reticulum (ER) stress and LXRα can affect the metabolism of cholesterol. However, whether ER stress can modulate ch...

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Detalhes bibliográficos
Publicado no:Nutrients
Main Authors: Wang, Tian, Zhao, Yiyang, You, Zhongsheng, Li, Xiatian, Xiong, Mingdi, Li, Hua, Yan, Nianlong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601278/
https://ncbi.nlm.nih.gov/pubmed/33050595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu12103088
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