Liver LXRα expression is crucial for whole body cholesterol homeostasis and reverse cholesterol transport in mice

Liver X receptors (LXRα and LXRβ) are important regulators of cholesterol and lipid metabolism, and their activation has been shown to inhibit cardiovascular disease and reduce atherosclerosis in animal models. Small molecule agonists of LXR activity are therefore of great therapeutic interest. Howe...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Zhang, Yuan, Breevoort, Sarah R., Angdisen, Jerry, Fu, Mingui, Schmidt, Daniel R., Holmstrom, Sam R., Kliewer, Steven A., Mangelsdorf, David J., Schulman, Ira G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336978/
https://ncbi.nlm.nih.gov/pubmed/22484817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59817
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars