Epac1 Is Crucial for Maintenance of Endothelial Barrier Function through A Mechanism Partly Independent of Rac1

Epac1 (exchange protein activated by cAMP) stabilizes the endothelial barrier, but detailed studies are limited by the side effects of pharmacological Epac1 modulators and transient transfections. Here, we compare the key properties of barriers between endothelial cells derived from wild-type (WT) a...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: García-Ponce, Alexander, Schuster, Katharina, Døskeland, Stein-Ove, Reed, Rolf K., Curry, Fitz-Roy E., Waschke, Jens, Radeva, Mariya Y.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601253/
https://ncbi.nlm.nih.gov/pubmed/32992982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9102170
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