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Inclusion Complex of Docetaxel with Sulfobutyl Ether β-Cyclodextrin: Preparation, In Vitro Cytotoxicity and In Vivo Safety

Docetaxel (DTX), as a first-line anti-tumor drug, has been studied for decades for its diverse bioactivities. However, DTX presents poor solubility in water, low bioavailability and serious toxic side effects which has hindered its application in the clinic. To address these problems, docetaxel-sulf...

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Bibliografiske detaljer
Udgivet i:Polymers (Basel)
Main Authors: Ren, Lili, Yang, Xiaolong, Guo, Weilu, Wang, Jin, Chen, Guoguang
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601231/
https://ncbi.nlm.nih.gov/pubmed/33066097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/polym12102336
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