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Sulfobutyl Ether(7) β-Cyclodextrin (SBE(7) β-CD) Carbamazepine Complex: Preparation, Characterization, Molecular Modeling, and Evaluation of In Vivo Anti-epileptic Activity

The objective of the present investigation was to study the ability of sulfobutyl ether(7)-β-cyclodextrin to form an inclusion complex with carbamazepine, an anti-epileptic drug with poor water solubility. The formation of the complex was carried out using the industrially feasible spray-drying meth...

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Détails bibliographiques
Auteurs principaux: Jain, Ankitkumar S., Date, Abhijit A., Pissurlenkar, Raghuvir R. S., Coutinho, Evans C., Nagarsenker, Mangal S.
Format: Artigo
Langue:Inglês
Publié: Springer US 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225538/
https://ncbi.nlm.nih.gov/pubmed/21918921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-011-9685-z
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