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Sulfobutyl Ether(7) β-Cyclodextrin (SBE(7) β-CD) Carbamazepine Complex: Preparation, Characterization, Molecular Modeling, and Evaluation of In Vivo Anti-epileptic Activity
The objective of the present investigation was to study the ability of sulfobutyl ether(7)-β-cyclodextrin to form an inclusion complex with carbamazepine, an anti-epileptic drug with poor water solubility. The formation of the complex was carried out using the industrially feasible spray-drying meth...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer US
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3225538/ https://ncbi.nlm.nih.gov/pubmed/21918921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-011-9685-z |
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