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Inclusion Complex of Docetaxel with Sulfobutyl Ether β-Cyclodextrin: Preparation, In Vitro Cytotoxicity and In Vivo Safety

Docetaxel (DTX), as a first-line anti-tumor drug, has been studied for decades for its diverse bioactivities. However, DTX presents poor solubility in water, low bioavailability and serious toxic side effects which has hindered its application in the clinic. To address these problems, docetaxel-sulf...

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Bibliographic Details
Published in:Polymers (Basel)
Main Authors: Ren, Lili, Yang, Xiaolong, Guo, Weilu, Wang, Jin, Chen, Guoguang
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601231/
https://ncbi.nlm.nih.gov/pubmed/33066097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/polym12102336
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