Evi1 Counteracts Anti-Leukemic and Stem Cell Inhibitory Effects of All-Trans Retinoic Acid on Flt3-ITD/Npm1c-Driven Acute Myeloid Leukemia Cells

All-trans retinoic acid (atRA) has a dramatic impact on the survival of patients with acute promyelocytic leukemia, but its therapeutic value in other types of acute myeloid leukemia (AML) has so far remained unclear. Given that AML is a stem cell-driven disease, recent studies have addressed the ef...

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Vydáno v:Biomedicines
Hlavní autoři: Nguyen, Chi Huu, Grandits, Alexander M., Vassiliou, George S., Staber, Philipp B., Heller, Gerwin, Wieser, Rotraud
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7600968/
https://ncbi.nlm.nih.gov/pubmed/32998330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8100385
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