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Evi1 Counteracts Anti-Leukemic and Stem Cell Inhibitory Effects of All-Trans Retinoic Acid on Flt3-ITD/Npm1c-Driven Acute Myeloid Leukemia Cells

All-trans retinoic acid (atRA) has a dramatic impact on the survival of patients with acute promyelocytic leukemia, but its therapeutic value in other types of acute myeloid leukemia (AML) has so far remained unclear. Given that AML is a stem cell-driven disease, recent studies have addressed the ef...

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Publicado en:Biomedicines
Autores principales: Nguyen, Chi Huu, Grandits, Alexander M., Vassiliou, George S., Staber, Philipp B., Heller, Gerwin, Wieser, Rotraud
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7600968/
https://ncbi.nlm.nih.gov/pubmed/32998330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8100385
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