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Evi1 Counteracts Anti-Leukemic and Stem Cell Inhibitory Effects of All-Trans Retinoic Acid on Flt3-ITD/Npm1c-Driven Acute Myeloid Leukemia Cells

All-trans retinoic acid (atRA) has a dramatic impact on the survival of patients with acute promyelocytic leukemia, but its therapeutic value in other types of acute myeloid leukemia (AML) has so far remained unclear. Given that AML is a stem cell-driven disease, recent studies have addressed the ef...

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Détails bibliographiques
Publié dans:Biomedicines
Auteurs principaux: Nguyen, Chi Huu, Grandits, Alexander M., Vassiliou, George S., Staber, Philipp B., Heller, Gerwin, Wieser, Rotraud
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7600968/
https://ncbi.nlm.nih.gov/pubmed/32998330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8100385
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