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Evi1 Counteracts Anti-Leukemic and Stem Cell Inhibitory Effects of All-Trans Retinoic Acid on Flt3-ITD/Npm1c-Driven Acute Myeloid Leukemia Cells

All-trans retinoic acid (atRA) has a dramatic impact on the survival of patients with acute promyelocytic leukemia, but its therapeutic value in other types of acute myeloid leukemia (AML) has so far remained unclear. Given that AML is a stem cell-driven disease, recent studies have addressed the ef...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Nguyen, Chi Huu, Grandits, Alexander M., Vassiliou, George S., Staber, Philipp B., Heller, Gerwin, Wieser, Rotraud
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7600968/
https://ncbi.nlm.nih.gov/pubmed/32998330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8100385
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