Mechanisms of Acquired BRAF Inhibitor Resistance in Melanoma: A Systematic Review

SIMPLE SUMMARY: Patients with advanced melanoma are often treated with v-raf murine sarcoma viral oncogene homolog B1 (BRAF) inhibitors. Although these agents prolong life, patients inevitably develop resistance and their cancer progresses. This review examines all of the potential ways that melanom...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Proietti, Ilaria, Skroza, Nevena, Bernardini, Nicoletta, Tolino, Ersilia, Balduzzi, Veronica, Marchesiello, Anna, Michelini, Simone, Volpe, Salvatore, Mambrin, Alessandra, Mangino, Giorgio, Romeo, Giovanna, Maddalena, Patrizia, Rees, Catherine, Potenza, Concetta
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7600801/
https://ncbi.nlm.nih.gov/pubmed/33003483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12102801
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