Mechanisms of Acquired BRAF Inhibitor Resistance in Melanoma: A Systematic Review

SIMPLE SUMMARY: Patients with advanced melanoma are often treated with v-raf murine sarcoma viral oncogene homolog B1 (BRAF) inhibitors. Although these agents prolong life, patients inevitably develop resistance and their cancer progresses. This review examines all of the potential ways that melanom...

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發表在:Cancers (Basel)
Main Authors: Proietti, Ilaria, Skroza, Nevena, Bernardini, Nicoletta, Tolino, Ersilia, Balduzzi, Veronica, Marchesiello, Anna, Michelini, Simone, Volpe, Salvatore, Mambrin, Alessandra, Mangino, Giorgio, Romeo, Giovanna, Maddalena, Patrizia, Rees, Catherine, Potenza, Concetta
格式: Artigo
語言:Inglês
出版: MDPI 2020
主題:
Review
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7600801/
https://ncbi.nlm.nih.gov/pubmed/33003483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12102801
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