Mechanisms of Acquired BRAF Inhibitor Resistance in Melanoma: A Systematic Review

SIMPLE SUMMARY: Patients with advanced melanoma are often treated with v-raf murine sarcoma viral oncogene homolog B1 (BRAF) inhibitors. Although these agents prolong life, patients inevitably develop resistance and their cancer progresses. This review examines all of the potential ways that melanom...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Proietti, Ilaria, Skroza, Nevena, Bernardini, Nicoletta, Tolino, Ersilia, Balduzzi, Veronica, Marchesiello, Anna, Michelini, Simone, Volpe, Salvatore, Mambrin, Alessandra, Mangino, Giorgio, Romeo, Giovanna, Maddalena, Patrizia, Rees, Catherine, Potenza, Concetta
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7600801/
https://ncbi.nlm.nih.gov/pubmed/33003483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12102801
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