Mechanisms of Acquired BRAF Inhibitor Resistance in Melanoma: A Systematic Review

SIMPLE SUMMARY: Patients with advanced melanoma are often treated with v-raf murine sarcoma viral oncogene homolog B1 (BRAF) inhibitors. Although these agents prolong life, patients inevitably develop resistance and their cancer progresses. This review examines all of the potential ways that melanom...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Proietti, Ilaria, Skroza, Nevena, Bernardini, Nicoletta, Tolino, Ersilia, Balduzzi, Veronica, Marchesiello, Anna, Michelini, Simone, Volpe, Salvatore, Mambrin, Alessandra, Mangino, Giorgio, Romeo, Giovanna, Maddalena, Patrizia, Rees, Catherine, Potenza, Concetta
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7600801/
https://ncbi.nlm.nih.gov/pubmed/33003483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12102801
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