Retinoblastoma Tumor Suppressor Protein Roles in Epigenetic Regulation

SIMPLE SUMMARY: Loss of function of the retinoblastoma gene (RB1) is the rate-limiting step in the initiation of both the hereditary and sporadic forms of retinoblastoma tumor. Furthermore, loss of function of the retinoblastoma tumor suppressor protein (pRB) is frequently found in most human cancer...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Guzman, Frederick, Fazeli, Yasamin, Khuu, Meagan, Salcido, Kelsey, Singh, Sarah, Benavente, Claudia A.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7600434/
https://ncbi.nlm.nih.gov/pubmed/33003565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12102807
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